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Remdesivir treatment. Time to death within one month of remdesivir treatment initiation (or corresponding medical facility day for matched control people) and time to hospital discharge with time to death as a competing occasion. Associations in between remdesivir treatment and these results were examined using Cox proportional risks regression in the matched friend.

3%) of whom got remdesivir treatment (2238 guys [94. 3%]; imply [SD] age, 67. 8 [12. 8] years) and 3524 (59. 7%) of whom never ever received remdesivir treatment (3302 males [93. 7%]; imply [SD] age, 67. 0 [14. 4] years). After  outdoors  matching, the analysis consisted of 1172 remdesivir recipients and 1172 controls, for a final matched friend of 2344 individuals.

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6 [14. 2] years vs 67. 5 [14. 1] years), sex (1101 guys [93. 9%] vs 1101 males [93. 9%], dexamethasone usage (559 [47. 7%] vs 559 [47. 7%], admission to the extensive care unit (242 [20. 7%] vs 234 [19. 1%], and mechanical ventilation use (69 [5. 9%] vs 45 [3.

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Standardized differences were less than 10% for all steps. Remdesivir treatment was not associated with 30-day mortality (143 remdesivir recipients [12. 2%] vs 124 controls [10. 6%]; log rank P =. 26; changed threat ratio [HR], 1. 06; 95% CI, 0. 83-1. 36). Outcomes were comparable for people receiving vs not receiving dexamethasone at remdesivir initiation (dexamethasone recipients: changed HR, 0.

64-1. 35; nonrecipients: changed HR, 1. 19; 95% CI, 0. 84-1. 69). Remdesivir receivers had a longer typical time to healthcare facility discharge compared to matched controls (6 days [interquartile variety, 4-12 days] vs 3 days [interquartile range, 1-7 days]; P.